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汤 强

发布者: [发表时间]:2018-04-17 [来源]: [浏览次数]:

汤强,男,副教授,心脑血管专业方向。1999年毕业于同济医科大学临床医疗系,获学士学位;2003年获华中科技大学同济医学院(原同济医科大学)药理学硕士学位,2007年6月获博士学位。曾于2005年12月赴香港大学心血管内科进修学习,并于2009年9月赴美国纽约洲奥尔巴尼医学院心血管研究中心从事博士后研究工作。自1999年以来,先后从事心脑血管生理与病理生理,药理等方面的研究,主持国家自然科学研究基金(青年基金)一项(No.81102439),参与国家自然科学基金课题多项(No.81102438, No.81102691, No.81000080,No.30901572和No.30801396等),曾于Circulation,Br J Pharmacol,Biochemical Pharmacology发表论文多篇。曾指导研究生连续两次获得国家硕士奖学金。

发表的论文如下:

1)QuanXiao-Qin, Li Song, Liu Rui, Zheng Kai, Wu Xiao-Fen, Tang Qiang.A meta-analytic review of prevalence for Brugada ECG patterns and the risk for death. Medicine (Baltimore).2016 Dec;95(50):e5643.

2)Huan Wang, Hong-fei Wang, Hao Zhang, Chen Wang, Yu-fang Chen, Rong Ma, Jizhou Xiang, Xin-ling Du,Qiang Tang. Inhibitory effects of hesperetin on Nav1.5 channels stably expressed in HEK 293 cells and on the voltage-gated cardiac sodium current in human atrial myocytes. Acta Pharmacologica Sinica. 2016 Dec;37(12):1563-1573。

3)Wang Huan, Wang Hong-fei, Wang Chen, Chen Yu-Fang, Ma Rong, Xiang Ji-zhou, Du Xin-ling, Tang Qiang.Inhibitory effects of hesperetin on Kv1.5 potassium channels stably expressed in HEK 293 cells and ultra-rapid delayed rectifier K+ current in human atrial myocytes. Eur J Pharmacol. 2016; Oct,789:98-108.

4)Wang Chen, Wang Huan, XiaoJun-hua, WangJia-ling, Xiang Ji-zhou, Tang Qiang. Inhibitory effects of neferine on Nav1.5 channels expressed in HEK293 cells. J Huazhong Univ Sci Technolog Med Sci. 2016; Aug,36(4):487-493.

5)Yu-fang CHEN, Chen WANG, Rui ZHANG, Huan WANG, Rong MA, Si JIN,Ji-zhou XIANG,Qiang TANG.TacrolimusInhibitsVasoconstriction byIncreasing Ca2+Sparks inRatAorta,Journal ofHuazhong University of Science and Technology[Medical Sciences]. 2016,Feb,36(1):8-13.

6)Chen WANG, Yu-fang CHEN, Xiao-Qing QUAN,Huan WANG, Rui ZHANG, Jun-hua XIAO,Jia-ling WANG, Cun-Tai ZHANG,Ji-zhou XIANG,Qiang TANG.Effects of neferine on Kv4.3potassium channelsand rabbit cardiac electrophysiology. Acta Pharmacologica Sinica. 2015,Dec;36(12):1451-1461。

7)Zheng YM,Park SW,Stokes L,Tang Q,Xiao JH,Wang YX。Distinct activity of BK channel β1 subunit in cerebral and pulmonary artery smooth muscle cells.Am J Physiol Cell Physiol.2013,304(8):C780-9.

8)Dong MQ, Sun HY,Tang Q,Tse HF, Lau CP,Li GR. Regulation of human cardiac KCNQ1/KCNE1 channel by epidermal growth factor receptor kinase.Biochim Biophys Acta.2010,1798(5):995-1001.

9)Ma R, Xiong N, Huang C,Tang Q, Hu B, Xiang J, Li G. Erythropoietin protects PC12 cells from beta-amyloid(25-35)-induced apoptosis via PI3K/Akt signaling pathway。Neuropharmacology. 2009,56(6-7):1027-1034。

10)Li G,Ma R, Huang C,Tang Q, Fu Q, Liu H, Hu B, Xiang J. Protective effect of erythropoietin on beta-amyloid-induced PC12 cell death through antioxidant mechanisms. Neurosci Lett. 2008,442(2):143-7

11)Tang Q,Li ZQ, Li W, et al.The 5-HT(2) antagonist ketanserin is an open channel blocker of human cardiac ether-à-go-go-related gene (hERG) potassium channels.Br J Pharmacol. 2008,155(3):365-373。

12)Li GR, Wang HB, Qin GW, Jin MW,Tang Q, et al.Acacetin, a natural flavone, selectively inhibits human atrial repolarization potassium currents and prevents atrial fibrillation in dogs. Circulation. 2008;117(19):2449-2457。

13)Tang Q,Jin MW,Xiang JZ,Dong MQ,Sun HY,Lau CP,Li GR. The membrane permeable calciumchelator BAPTA-AMdirectly blocks human ether a-go-gorelatedgene potassium channels stably expressed in HEK 293 cells.Biochemical Pharmacology2007,74(11):1596-1607.

14)J.J.Li,Q.Tang,Y.Li, B.R.Hu, Z.Y.Ming, Q.Fu, J.Q.Qian, J.Z.Xiang. Role of oxidative stress in the apoptosis of hepatocellular carcinoma induced by combination of arsenic trioxide and ascorbic acid, Acta Pharmacol.Sin., 2006,27,1078-1084.(Equal contribution)

15)汤强,谭艳,赵锦花,胡本容,杨德隆,陈汇,向继洲. 氟罗沙星片人体生物等效性研究. 中国医院药学杂志,2006,26(9),1069-1072.

16)汤强胡本容谭艳马嵘付琴陈建国向继洲.hβ-CGRP预孵育对H2O2致心肌细胞内游离钙离子浓度增加的影响.华中科技大学学报(医学版)2006,35(5): 570-572

17)Tan Y,Tang Q, Hu BR, Xiang JZ.Antioxidant properties of berberine on cultured rabbit corpus cavernosum smooth muscle cells injured by hydrogen peroxide.Acta Pharmacol Sin. 2007, 28(12):1914-1918.

18)Long-rui PAN,Qiang TANG,Qin FU, Ben-rong HU, Ji-zhou XIANG, Jia-qing QIAN.Roles of nitric oxide in protective effect of berberine in ethanol-induced gastric ulcer mice.Acta Pharmacologica Sinica.2005,26(11):1281-1408

19)彭芳;汤强;胡本容;向继洲。氧化应激在乙醇诱导内皮细胞凋亡中的作用。医药导报,2008(2):

20)杨柳,汤强胡本容向继洲.酒精对兔阴茎海绵体的舒张效应及其作用机制. 中华男科学杂志.2007,13(10):910–914.

21)谭艳汤强胡本容向继洲. 小檗碱对离体阴茎海绵体NO-cGMP信号通路的调控. 中国药理学通报,2005,21(4):435-440

22)谭艳汤强胡本容向继洲. 小檗碱对离体家兔阴茎海绵体cGMP和cAMP水平的影响. 中华男科学杂志,2005,11(6):406-408

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