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刘慧

发布者: [发表时间]:2018-10-12 [来源]: [浏览次数]:

 

1326

刘慧,女,博士,副教授,学系副主任,湖北省药理学会常务理事,“中国药理学会施维雅青年药理学工作者奖”获得者,2003~2005年香港大学心血管研究所访问学者,2012~2014年香港大学李嘉诚医学院生理学系博士后人员。长期从事药理学的教学与科研工作,主持及参与多项国家自然科学基金项目、国家科技部科技攻关项目。

E-mail:liuh@hust.edu.cn

研究方向心血管和代谢性疾病及肿瘤靶点研究与药物开发

代表性论文(仅列第一作者和*通讯作者文章):

1. Han Y, Wu JZ, Shen JZ, Chen L, He T, Jin MW,Liu H*.Pentamethylquercetin induces adipose browning and exerts beneficial effects in 3T3-L1 adipocytes and high-fat diet-fed mice.Sci Rep. 2017,7:1123

2. Liu H, Yang L, Wu HJ, Chen KH, Lin F, Li G, Sun HY, Xiao GS, Wang Y, Li GR. Water-soluble acacetin prodrug confers significant cardioprotection against ischemia/reperfusion injury.Sci Rep.2016,7(6):36435

3. Liu H, Wang YJ, Yang L, Zhou M, Jin MW, Xiao GS, Wang Y, Sun HY, Li GR. Synthesis of a highly water-soluble acacetin prodrug for treating experimental atrial fibrillation in beagle dogs.Sci Rep. 2016,10(6):25743

4. Liu H, Yang L, Chen KH, Sun HY, Jin MW, Xiao GS, Wang Y, Li GR. SKF-96365 blocks human ether-à-go-go-related gene potassium channels stably expressed in HEK 293 cells.Pharmacol Res. 2016, 104:61-9

5. Yang L,Liu H*, Sun HY, Li GR. Intravenous Anesthetic Propofol Inhibits Multiple Human Cardiac Potassium Channels.Anesthesiology. 2015, 122(3):571-84

6. Feng M, Xiang JZ, Ming ZY, Fu Q, Ma R, Zhang QF, Dun YY, Yang L,Liu H*. Activation of epidermal growth factor receptor mediates reperfusion arrhythmias in anaesthetized rats.Cardiovasc Res. 2012;93(1): 60-68

7. Liu H, Yang L, Jin MW, Sun HY, Huang Y, Li GR. The selective estrogen receptor modulator raloxifene inhibits cardiac delayed rectifier potassium currents and voltage-gated sodium current without QTc interval prolongation.Pharmacol Res. 2010, 62(5):384-90

8. Liu H, Sun HY, Lau CP, Li GR. Regulation of voltage-gated cardiac sodium current by epidermal growth factor receptor kinase in guinea pig ventricular myocytes.J Mol Cell Cardiol. 2007, 42(4) :760-768

9. Liu H, Jin MW, Xiang JZ, Huang Y, Sun HY, Chiu SW, Lau CP, Li GR.Raloxifene inhibits transient outward and ultra-rapid delayed rectifier potassium currents in human atrial myocytes.Eur J Pharmacol. 2007, 563(1-3):61-8